What causes germicide rebound?

Germicide rebound typically refers to the phenomenon where a dialyzer may release previously bound germicide back into the dialysate after it has been primed or used. This can lead to potential complications if the dialysate becomes contaminated. The primary cause of this rebound effect is often related to inadequate dialyzer priming. When a dialyzer is not adequately primed, residual germicide can remain within the fibers or the casing. As the dialysis process begins, changes in pressure and flow can cause this trapped germicide to be released back into the dialysate, leading to the phenomenon known as germicide rebound.

Proper priming ensures that all residual disinfectants are thoroughly washed out from the dialyzer, thus minimizing the risk of rebound and ensuring patient safety. Ensuring that each step of the priming process is conducted thoroughly is essential for effective dialyzer preparation and preventing the residual contamination of the dialysis fluid.