Short frequent hemodialysis treatments with high BUN are aimed at preventing:

Short frequent hemodialysis treatments with high blood urea nitrogen (BUN) levels are designed to prevent dialysis disequilibrium syndrome. This syndrome can occur when there is a rapid change in solute levels in the blood during dialysis, often leading to an imbalance in fluid and electrolytes, which can cause neurological symptoms. In patients who receive more frequent sessions of hemodialysis, the gradual removal of toxins, such as urea, helps to maintain a more stable equilibrium between the blood and dialysate, reducing the risk of rapid shifts in osmotic gradients and minimizing the potential for dialysis disequilibrium syndrome to develop.

In contrast, while cardiac arrhythmias and excessive anticoagulation can be important considerations in the hemodialysis process, they are typically managed with different strategies than those focusing specifically on the frequency and duration of treatments. Rapid decreases in hematocrit, which could arise due to excessive fluid removal or other factors, are not the primary concern addressed by short frequent hemodialysis aimed particularly at regulating BUN levels.